Endocrine Abstracts

Section 1: Case history An 86 year old female presented to hospital after being found on the floor and had profound lower limb oedema. She was treated for a urinary tract infection and possible heart failure. On examination she had significant hirsutism and bruised skin. She had a past medical history of BCC removal and primary hyperparathyroidism. Her ECOG performance status was 1–2. There was a family history of pancreatic cancer (father) and pancreatic neuroendocrine tumour...

A 41-year-old lady presented with a long history of very severe premenstrual dysphoria, commencing 2 weeks prior menstruation. Her symptoms included behavioural problems and in particular aggression, impaired memory, palpitation, bloating and diarrhoea. She also experience cyclical left head and left eye pain without visual symptoms. She was para 3+0 with a past medical history of polycystic ovary syndrome, eventually treated by ovarian diathermy. During pregnancy her symptoms...

Background: Pituitary metastases are a rare occurrence, accounting for just 0.4% of intracranial metastatic tumours and are most often associated with breast and lung malignancies. The vast majority of lesions are asymptomatic and due to the predilection of metastasis to the posterior lobe of the pituitary gland, clinical presentation with anterior pituitary insufficiency is uncommon and rarely reported in literature.Case summary: A 51-year old male with...

Background: The incidental adrenal lesion, coined ‘incidentaloma’, is a common radiological finding, necessary of further investigation and diagnosisAims: This is a retrospective observational study which aims to identify the prevalence of incidentaloma in CT scans of the abdomen and pelvis in the Brighton & Sussex University Hospital’s Trust. Our additional objective is to assess the adequacy of incidentaloma management throu...

A 60-year-old woman presented with 2 months of aching limbs and 2 weeks of nausea and a left sided neck mass. She was clinically euthyroid with a 5 cm non-tender left thyroid nodule. There was no cervical lymphadenopathy and the remainder of the examination was unremarkable. There was no family history of any endocrine disorder.Investigations showed serum TSH concentration 5.94 μ/l and serum free T4 concentration 12 pmol/l. Thyroid peroxi...